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By weeks 4 to 6 at a stable dose, most patients report significant improvement or complete resolution of symptoms

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Injection is the only route with meaningful animal pharmacokinetic data behind it

At the highest dose of retatrutide: Average body-weight loss for patients who completed the study was 28.7% Average body-weight loss among all participants (including dropouts) was 23.7% To put this into perspective: Wegovys typical weight loss is around 15% Zepbounds/Mounjaros Phase 3 results showed 22.5% Retatrutides own Phase 2 produced 24.2% at 48 weeks Many bariatric surgery patients lose 2535% of body weight This means retatrutides weight loss in Phase 3 is approaching the lower end of bariatric surgery, while requiring only a once-weekly injection