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Methylation analysis in monozygotic twins with treatment-resistant schizophrenia and discordant responses to clozapine

However, low to moderate levels of ROS can promote cancer cell survival and metastasis pathways through DNA damage-induced genomic instability, epigenetic regulation, metabolic reprogramming, and generation of pro-inflammatory and pro-tumorigenic microenvironment in a context-dependent manner [8, 12, 13, 26]

ICU admission represents an excellent opportunity to perform a graded challenge, since the patient is being intensely monitored with the ability to immediately treat anaphylaxis