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Figure 2 For oral delivery, marker-free mushrooms can be engineered to express therapeutic proteins fused to transmucosal carriers, such as CTB, and to include furin-cleavage motifs for post-absorption activation

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Ansari, H.U.H

This section discusses this common pathology by dividing it into four interconnected mechanistic axes: (i) a shared fibrosis-inflammation signal axis, (ii) the formation of a fibrotic microenvironment due to the disruption of immune homeostasis, (iii) oxidative stress-based microenvironmental lock-in, and (iv) upstream regulation failure due to barrier dysfunction