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A patient using GLP-1 without medical supervision may miss: contraindication screening (thyroid cancer history, pancreatitis history), baseline metabolic assessment, dose titration management, monitoring for pregnancy (GLP-1 medications require discontinuation before conception), monitoring for side effects requiring intervention, and crucially, guidance on protein intake and resistance training to preserve lean mass during weight loss

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Some of these medications have also been shown to reduce the amount of insulin that people with type 2 diabetes may require