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The LEADER, REWIND, and SUSTAIN-6 trials of respective liraglutide 1.8 mg/daily (or maximum tolerated dose), once-weekly dulaglutide 1.5 mg, and once-weekly semaglutide 0.5 mg or 1.0 mg administration in patients with type 2 diabetes and cardiovascular disease or risk factors found decreased hazard ratios ranging from 0.74 to 0.88 for the primary composite endpoint first occurrence of death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke [112114]

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The therapy is minimally invasive, and the risk of side effects is low when used appropriately

By regulating melanin production, it also helps fade dark spots and uneven tone, which gives the skin a smoother, brighter, more refreshed look