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Lastly, we leveraged our single-cell mass cytometry approach (Supplementary Fig

A board-certified Orthopaedic Surgeon in General and Sports Medicine, he served as Chief of Surgery at University Hospitals Conneaut Medical Center, Site Director of the University Orthopaedic Residency Program at University Hospitals, and Director of The Ohio Bone & Joint Institute

Due to the highly amyloidogenic nature of endogenous human insulin, researchers took inspiration from the proline residues in rat insulin, which are highly homologous but not amyloidogenic (known to disrupt the secondary structure), and incorporated them into the human insulin sequence to develop Pramlintide

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