liraglutide glp 1 analogue Five Unexpected New Uses for GLP-1 Receptor Agonists FDA Approves Generic Version of

However, this model has come into question, as evidence demonstrating local, intra-islet GLP-1 production has advanced the competing hypothesis that the incretin activity of GLP-1 may reflect paracrine signaling of GLP-1 from alpha-cells on GLP-1Rs on beta-cells

Glucagon-like peptide-1 receptors in the brain: controlling food intake and body weight Text PDF Abstract The peptide hormone glucagon-like peptide-1 (GLP-1) enhances glucose-induced insulin secretion and inhibits both gastric emptying and glucagon secretion

This suggests that the impact on synaptic plasticity might be long-term

But I think the notion, I think it's the same for example with metformin, even though it gives less weight loss because that has also been tried in both people with diabetes and people without diabetes