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Septerna has developed a native complex platform that can reconstitute the GLP-1 receptor within an artificial lipid bilayer, complexed with combinations of drug and internal cell signalling molecules, which replicates the dynamics of the signalling process at scale

Efficacy Results Key efficacy results of Study 023 are summarized in Table 2

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Researchers point to several reasons for this variation, including differences between specific GLP-1 medications, individual mental health history, the presence of eating disorders or mood disorders, and differences in dosage, duration of use, and overall health