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Three of the sequences are very similar to each other (~96% sequence identity) and may represent transcripts derived from different homeologous alleles of the same gene (Figure S4)

As our results show that SNIP1 and CDK11 act together in spliceosome activation and CDK11 is overexpressed in many cancers 8,104,105,106,107,108 , the CDK11/P-SF3B1/SNIP1 pathway may be a novel oncogenic driver of splicing-dependent cancers 109 , warranting further investigation

What Glutathione Does in the Body What Glutathione Does in the Body Glutathione is often called the master antioxidant because it helps protect cells from oxidative stress

Int J Cancer 1996;68:71622