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GLP-1 receptor agonists (semaglutide, liraglutide, dulaglutide) and the dual agonist tirzepatide carry the evidence: STEP for semaglutide (NEJM 2021), SURMOUNT for tirzepatide (NEJM 2022), and SURMOUNT-OSA for tirzepatide in obstructive sleep apnea (NEJM 2024)
The traditional way of getting weight loss medication often involves long wait times for specialist appointments and repeated trips to the doctors office
Research in Obesity shows that patients on GLP-1 drugs who consumed fewer than 80 grams of protein daily lost 15-20% more lean muscle mass compared to those meeting protein targets
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