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A few weeks ago, I saw an interesting article with the headlines with something in the effect of Ultra marathon GLP-1 Agonists and Risk of NAION: Does Study Number 5 Add Anything New

10.1016/0026-0495(93)90285-V 43 FryburgD

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Because they are subject to a lower regulatory standard, compounded drugs should only be distributed to health care facilities or dispensed to patients to fulfill the needs of patients whose medical needs cannot be met by an FDA-approved drug. Talk to your health care provider about compounded weight loss medications or other options Ultimately, deciding whether to use a compounded GLP-1RA is a personal choice that should involve a conversation between the patient and their prescriber