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These mutations alter the activity of the encoded enzymes such that instead of converting isocitrate to 2-oxoglutarate (-ketoglutarate), while also generating NADPH, the mutant IDH enzymes reduce 2-oxoglutarate (-ketoglutarate) to 2-hydroxyglutarate (2-HG) while simultaneously oxidizing NADPH to NAPD +
At AgeWell Medicine & Aesthetics, we specialize in personalized age management and hormone optimization to help you look and feel your best at every stage of life
Given its importance, maintaining optimal levels is essential
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