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As proof, ASCT2 ( SLC1A5 ) knockdown in osteosarcoma and cervical cancer cells can induce upregulation of SNAT1 ( SLC38A1 ) (Broer et al., Glutamine catabolism, namely glutaminolysis, begins with its conversion to glutamate, which is catalyzed by the glutaminase (GLS) (Hassanein et al., 2013)

This complexity and the broad spectrum of symptoms make managing and treating long COVID particularly challenging, underscoring the need for innovative approaches and therapies

ASS1 as a novel tumor suppressor gene in myxofibrosarcomas: aberrant loss via epigenetic DNA methylation confers aggressive phenotypes, negative prognostic impact, and therapeutic relevance

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