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In some embodiments, an otic high viscosity formulation or device is administered in combination with an external otic intervention, e.g., a surgical procedure including but not limited to middle ear surgery, inner ear surgery, typanostomy, cochleostomy, labyrinthotomy, mastoidectomy, stapedectomy, stapedotomy, endolymphatic sacculotomy, or the like

In a statement, Zealand CMO David Kendali said that the company is certainly disappointed by the rejection but remains confident in glepaglutide and the evidence supporting its use in short bowel syndrome

Biol Psychiatry 2008;64:361-8

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