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Overall, these collective effects reduce food intake, increase satiety, and improve glucose metabolism, which can lead to robust weight loss, Rhodes says

Probiotics and gut health The gut microbiome plays a role in GLP-1 production, with certain bacterial strains, particularly Akkermansia muciniphila, associated with improved GLP-1 signaling

This creates a complex environment where Lilly must balance premium pricing with broader market access, especially as federal pricing negotiations are underway, signaling future cost pressure

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