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In the case of pronounced absorption disorders, for example as a result of gastritis or after removal of the small intestine, in Crohn's disease, diverticulosis and the so-called blind-loop syndrome, there is a gradual decrease in the vitamin B12 store in the liver, which can turn into a manifest vitamin B12 deficiency
When total B12 levels are difficult to interpret, measurement of holotranscobalamin (active B12), methylmalonic acid (MMA) , or homocysteine can provide a clearer picture of functional B12 status, though availability and interpretation vary (for example, MMA rises in renal impairment)
It's also important to inform the medical professional of any medications or supplements you are currently taking, as certain substances may interact with the ingredients in the injection
If you add 2.5mL instead of 3mL, your concentration jumps from 3.33mg/mL to 4mg/mL
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