Freezing reconstituted LIPO-C below 2C causes ice crystal formation that physically disrupts peptide structures, leading to precipitation and aggregation
Jaworski, K., Sarkadi-Nagy, E., Duncan, R
A fourth factor must now be built into the equation, namely, gene mutations that might favour the cytoplasmic presence of trypsin (97): the enzyme, as also chymotrysin, is readily inhibited by GSH via SH-SS exchange (24) should it break loose of constraint by SPINK1 (serine protease inhibitor Kazal type 1) (118), but less GSH is then available for control of electrophilic / oxidative stress and other vital roles (24, 30, 162)
A patient in India may have to spend about $200 a month when taking a weekly dose of 5 mg, subject to doctor's prescription