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Comprehensive in vitro models, including human skin S9 fraction, kidney S9 fraction and biological fluids, were used to investigate metabolic pathways

The program strives to ensure that: No female patient starts isotretinoin therapy if pregnant No female patient on isotretinoin therapy becomes pregnant This enhanced program is a SINGLE pregnancy risk management program for prescribing and dispensing all isotretinoin products (brand and generic products)

16.7% of skin radiance improvement after 1 use

One COA proves the blend is pharmaceutical grade. A meaningful blend assessment requires separate identity, quantity, ratio, impurity and stability evidence