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The STEP 4 withdrawal trial demonstrated that continued Semaglutide therapy was needed to maintain weight loss, as patients switched to placebo regained weight over 48 weeks (Rubino et al., JAMA 2021

Youssef, M

See guidance from reputable medical sources such as Mayo Clinic and expert summaries like the one from the Cleveland Clinic that explain B12 injections are not a proven weight-loss therapy for people with normal levels