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Unintentional weight loss exceeding clinical targets, inability to maintain adequate nutrition or hydration, or new or worsening heartburn or reflux symptoms that don't respond to over-the-counter treatments also warrant medical consultation

Mind Medicine Australia has continued its advocacy work, collaborating with the End Wise coalition to submit a rescheduling application in March 2025 to expand the use of psilocybin to include existential distress towards end-of-life