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In addition to its extensively studied actions in peripheral tissues, studies have evaluated the distribution of GLP-1R in the central nervous system (CNS) of rodents, non-human primates, and humans, showing that it is widely diffused to multiple CNS neurons including neurons of the arcuate nucleus (ARC), which are crucial for the control of energy balance (Fig

Take home message Fatty liver disease affects roughly one in three adults, yet most people dont know they have it until its discovered incidentally or has already progressed

The paradigm shift in whole diabetes care management and weight loss treatment has greatly influenced by GLP-1 analogues

In doing so, it activates pain responses while also regulating endocrine and REM sleep functions