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This fundamental difference in mechanism is why peptides have generated such interest despite the limitations of current evidence

doi: 10.3389/fnut.2025.1524627 Received 08 November 2024 Accepted 12 March 2025 Published 27 March 2025 Volume 12 - 2025 Edited by Denisse Castro-Eguiluz, National Council of Science and Technology (CONACYT), Mexico Reviewed by Syed Amir Ashraf, University of Hail, Saudi Arabia Suhas Siddheshwar, Pravara Rural College of Pharmacy, India Updates Copyright 2025 Ashrafpour and Ashrafpour

UPS interacts with deubiquitination and cellular autophagy, constituting a complex signaling regulatory network, which together regulate the development of renal diseases

In most cats and smaller dogs, 1 to 2 drops of the intranasal preparation administered once or twice daily are sufficient to control polyuria and polydipsia (see Table below)