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2 The mechanism of ferroptosis and iron homeostasis The critical molecular mechanism of ferroptosis involves regulating the balance between oxidative damage and antioxidant defense ( Intracellular iron accumulation is a key factor in ferroptosis, attributed to several fundamental processes of cellular metabolism

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One of the most common factors leading to COPD is a history of smoking, although other particulate matter exposures, chemical exposures, respiratory infections, chronic bronchitis, asthma, and genetic susceptibility can also affect incidence (Yoshida and Tuder, 2007

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