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Gut/GI protection Explored in preclinical research on protection of the gastrointestinal tract, reflecting its origin in a protein found in gastric juice

In the treatment groups combined (GSSG, GSH), these occurred in five patients (13.15%), which included three with pruritus (7.89%), one with erythema (2.63%), three with red spots (7.89%), and one with tiredness (2.63%)

Investigators administered BPC-157 by three routes intraperitoneal injection, oral administration in drinking water, and topical application as a thin cream layer with assessment over a 90-day post-injury period

Additional experimental models have investigated gastrointestinal fistula healing and tissue continuity restoration, again emphasizing the peptide's relevance to studies examining coordinated epithelial repair, vascular signaling, and inflammatory regulation within the digestive tract [1]