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Alcohol can interfere with the absorption of vitamin B12, reducing the effectiveness of the treatment

10.1038/nature05324 110

S., Zakher, B., Daeges, M., Pappas, M., & Chou, R

The top 10 screened hits formed complexes with ChaC1, with their binding free energies ranging between -96 to -80 kcal/mol, while their XP docking scores ranged between -8.4 to -8.1