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Intravenous GSH offers rapid systemic bioavailability and has demonstrated hepatoprotective properties in preclinical studies, including protection against ischemia-reperfusion injury during liver transplantation (56)

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In LC, depletion of ubiquitin-specific peptidase (USP)13 facilitates the transition from autophagy to ferroptosis in KRAS-mutant LUAD cells via the NRF2-p62-kelch like ECH associated protein 1 (KEAP1) axis (54)