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Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins

Nausea: The most common side effect generally mild-to-moderate, dose-related and diminishing over the first weeks

doi: 10.1007/s40265-020-01290-3

In such cases, high-dose folinic acid (Leucovorin) therapy is necessary for optimal brain function, particularly in autism, seizures, developmental delay, and movement disorders