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doi: 10.1007/s00467-015-3153-z

Some people develop blackheads and whiteheads, also known as comedones

One metabolite that contributes substantially to atherosclerosis and can be used to estimate cardiovascular risk is trimethylamine-N-oxide (TMAO) (164)

They disrupt fundamental cellular processes, including energy production, insulin signaling, glucose metabolism, and mitochondrial function, at times contributing to cognitive decline, fatigue, reduced ability to fight infections, and increased chronic disease risk