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In practice, this is explored using: cell based receptor assays for potency and efficacy signalling pathway readouts relevant to each receptor system comparative profiling against dual agonists and GLP-1 only comparators in some research discussions This is where researchers build the first layer of what it does in measurable terms: it activates three defined receptor systems that are already heavily studied in metabolic signalling

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PloS One, 13 (1), e0191030

The mean (SD) baseline bodyweight was 100.7 (21.1) kg, and the mean (SD) BMI was 36.1 (6.6) kg/m 2