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But those numbers shift when accounting for time on the waitlist showing HM3 survival was 5-8% higher than freedom from death or delisting due to deterioration for HTx candidates

471 According to the PAKT trial, the addition of the AKT inhibitor capivasertib to the first-line paclitaxel therapy for TNBC resulted in significantly longer PFS and OS, especially in tumors with PIK3CA/AKT1/PTEN alterations

This study aims to address known WD-associated cellular mechanisms in this cell culture model, increasing its significance for the development and testing of direct-acting therapeutic targets

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