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6.3 Irisin promotes neurogenesis and synaptic plasticity Depression is associated with reduced adult neurogenesis in the hippocampus, a reduction that can be alleviated or restored through chronic antidepressant treatment (Wang et al., 2008

Buyer benefit: Ensures homogenous distribution of all four peptides throughout the lyophilized cake, preventing "hot spots" of high concentration during reconstitution

Whether those studies establish a sufficient benefit-risk profile for human use through compounding pharmacies was the core scientific question, and the committee's majority answered yes over the objections of FDA scientists who answered no

Updated February, 2023