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Predraga Sikirica (Wydzia Medyczny w Zagrzebiu, 1991 ) Najczstsza dawka eksperymentalna w badaniach na zwierztach: 10 g/kg dootrzewnowo lub doustnie, codziennie Standardowe szlaki docelowe: angiogeneza VEGFR2 , syntaza NO , receptor serotoninowy 5-HT2A , receptor dopaminowy D2 Program kliniczny w Chorwacji zatrzymany w Phase 2 (choroba Crohna) WADA Prohibited List: wczenie w roku 2022 do kategorii S0 (Non-Approved Substances) rda referencyjne (PubMed) Sikiric P
Multiple peptide substances previously in a Category 2 position substances not yet fully evaluated but permitted for compounding under interim review status moved to a formally not-permitted posture pending further PCAC review
Nature 1972
If CagriSema is successful, it could increase confidence in other companies developing amylin-based therapies
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