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When individuals understand that mild GI symptoms may occur during early treatment, they are less likely to discontinue therapy prematurely

IL-1, IL-6, IL-8, IL-10, IFN-, TNF- and its relationship with lipid parameters in patients with major depression

Adding further complexity, regional heterogeneity in microglial phenotypes, such as differences between striatal and cortical microglia in PD, can influence treatment responses and must be carefully considered in the design of targeted therapies

In the NAFLD animal model, hepatic GLP-1R expression levels at the NAFL (8 weeks) and NASH (16 weeks) stages were downregulated, consistent with the data in humans