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WADA Prohibition The World Anti-Doping Agency has addressed MOTS-c in anti-doping guidance: While not explicitly listed by name in current prohibited substances lists, would likely fall under non-approved substances (Section S0) Detection methods under development for anti-doping testing programs Use by competitive athletes prohibited under WADA Code Exercise-mimetic properties create performance enhancement concerns USADA guidance specifically warns athletes that MOTS-c is not approved by FDA and remains prohibited for competitive sport use

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While it is generally effective and well-tolerated, it can cause side effects that users should understand