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In addition, MYC, a transcription factor that improves sensitivity to apoptosis stimulation, is upregulated, along with the activation of other apoptotic pathways, 26,124,125 causing irreversible damage or even death of cells
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2025 Retrospective Studies Retrospective studies analyze preexisting information, often patient records, to explore potential links between prior exposures and later outcomes
However, further studies are warranted to fully delineate the distinct pathophysiology of MetALD development, which is driven by both alcohol and metabolic dysfunction
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