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Tendon Research Applications Studies in Journal of Orthopaedic Research explored BPC-157s effects on tendon healing, demonstrating enhanced fibroblast proliferation, improved collagen organization, increased mechanical strength, and accelerated tendon-to-bone healing in experimental models

The indication for prophylactic pharmacotherapy depends on attack intensity (more than every 12 months) and severity (exceeding 2 days or requiring hospitalization), the impairment of the QoL (e.g., frequent school absences) and if attack treatments are ineffective or cause side effects

The translation of these findings requires cautious interpretation and further rigorous human studies to establish efficacy, safety, and optimal dosing

Morning versus evening is a matter of personal tolerability and lifestyle fit, not clinical superiority