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In addition, a volcano plot and K-means clustering heatmaps were used to show the distribution of significance and fold change of the DEPs between the Sema and HFD groups ( Figures 4C, D )

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In the postmenopausal phase of the study, treatment with soy plus Premarin resulted in DHEA-S levels that were 29 percent lower than the monkeys who ate soy without isoflavones (control group) and 35 percent lower than the group eating soy with isoflavones