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9 Challenges and limitations to compliance with GLP-1 RA therapy While GLP-1 RA therapies are highly effective for glycemic control and weight loss, real-world data indicate that many patients either discontinue or struggle to adhere to these treatments

Among these, obesity (defined by the WHO as a body mass index (BMI) 30 kg/m 2 ) [6], is characterized by low-grade inflammation driven by adipokine secretion from adipose tissue

Structural modulation of the gut microbiota and the relationship with body weight: compared evaluation of liraglutide and saxagliptin treatment

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