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The results of these studies have shown that administration of SILY could be associated with either weight loss or weight gain[28,32,69-71] depending on the disease model used

Mice that were given an mRNA vaccine expressing pre-fusion SARS-CoV-2 S protein developed neutralizing antibodies and S-protein-specific CD8 T cell responses that were protective against lung infection without evidence of immunopathology 116 , and neutralizing mAbs against the RBD of the S protein of SARS-CoV-2 reduced lung infection and cytokine release 117

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