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To reduce the risk of serious disease or death, a vaccine provides an initial first exposure to a weakened pathogen that cannot cause disease, but can still train the adaptive immune response to fight that particular pathogen
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Zonula occludens toxin (Zot, or zonulin), an enterotoxin secreted by intestinal epithelial cells following stimuli from diets or microbiota, was shown to be a potent regulator of TJ competency and intestinal barrier function
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