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We are seeing a drug that should only be prescribed under strict medical supervision being sold like an over-the-counter supplement, she said

For every kilogram of body weight lost, triglycerides typically decrease and HDL cholesterol increases

The difference in fat-to-muscle ratio is statistically significant and functionally important: preserving lean mass maintains resting metabolic rate, reduces post-diet weight regain risk, and sustains physical performance during weight loss

At eight years, the cumulative incidence of the primary endpoint was 21.7% (95% CI, 12.2-30.6) in the surgical group and 45.1% (95% CI, 27.7-58.4) in the nonsurgical group (adjusted HR [aHR], 0.40