lean mass loss semaglutide Beyond fat: Does affect mass? Weight loss and muscle loss.

Melanocortin receptors are widely expressed in the central and peripheral nervous system, and alpha-MSH analogs have demonstrated neuroprotective properties across multiple models

If imaging is needed, patients can get a referral

The title of the paper states the conclusion directly: Weight loss with GLP-1 medicines does not result in a disproportionate loss of muscle mass or function. Sarcopenia is not a synonym for lost some muscle. The 2019 European Working Group revision (EWGSOP2) consensus defines it as a syndrome of low muscle strength and impaired physical function

ScienceDirect, Bharathselvi, Muthuvel, Sayantan Biswas, et al