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In AD, glutamatergic and cholinergic synapses of the temporal lobe are affected first, followed by a spread to other regions (Picconi et al., 2005

The role of Epstein-Barr virus in the etiology of multiple sclerosis: a current review

But the primary concern is the risk of ochronosis, a rare but challenging condition where long-term overuse paradoxically causes darkening of the skin, says Francesa Lewis, MD, a board-certified dermatologist in Delray Beach, Florida

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