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SFN induces a pro-oxidative milieu in untransformed human T-cells ROS are ubiquitously generated and recognized as important signaling molecules for T-cell activation, but excessive ROS generation or prolonged exposure to high ROS concentrations impair T-cell functions ( 2 DCFDA and treated with SFN prior to flow cytometric analysis
Complementary work using green-derived CQDs synthesised from bread waste demonstrated efficient cellular internalisation and widespread cytoplasmic distribution in HT-29 and CT-26 colon carcinoma cells, enabling clear visualisation of subcellular features under fluorescence microscopy [95]
This, in turn, fosters the reprogramming of M1 into M2, thereby safeguarding immune homeostasis and averting excessive inflammatory reactions in RA (219)
2023 Nov;22(11):e13936
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