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In an interim analysis of the ongoing phase 3 Effect of Semaglutide in Subjects with Non-cirrhotic Non-alcoholic Steatohepatitis (ESSENCE) trial (NCT04822181), once-weekly semaglutide 2.4 mg demonstrated superiority versus placebo for improvement of histological activity and fibrosis in participants with MASH and moderate to advanced liver fibrosis 6

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Psychological factors such as stress, sleep quality, and emotional eating patterns can significantly influence outcomes

If your prescriber checks kidney function periodically, expect mild fluctuations