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Other warnings and precautions listed in the product monograph include benign and malignant neoplasms, slipped femoral epiphysis and progression of scoliosis (due to rapid growth), allergic reactions, and intracranial hypertension

The trials were well-designed, the results compelling

GLP-1 agonists are contraindicated in pregnancy

In particular, the categorization of patients based on molecular subtypes of -cell dysfunction not only refines our understanding of pathogenic mechanisms but also helps predict the efficacy of targeted interventions, including microbiome-modulating approaches and therapy with GLP1R agonists