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GABAergic transmission, which alcohol enhances to produce its sedative and anxiolytic effects, appears modulated by GLP-1 signaling

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When compared to the control group, TG contents in pancreatic tissue of rats in T2DM and T2DM + sham groups significantly increased, while it observably decreased after surgery in T2DM + RYGB and T2DM + EX-4 groups (Figure 6K)

And MOTS-c can promote glucose utilization, inhibit oxidative stress, activate NF-B to inhibit inflammation, and effectively protect coronary artery endothelial cell dysfunction (9)