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Net result: a serum half-life of approximately 20 to 30 hours in rodents versus 12 to 15 minutes for free native IGF-1

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For comparison, the modified GHRH analog CJC-1295 (specifically the version without DAC, which is what is commonly used in modern clinics) has a longer functional duration that keeps the GHRH stimulus present long enough for a more meaningful, sustained growth hormone pulse to occur

Missing MS/MS acquisition of the IHEVLAPGC * L peptide precursor at m/z 600.8077 was caused by a higher abundant interference at m/z 601.3123, overlapping with the peptide [M+1+2H] 2+ signal