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Caporaso JG, Kuczynski J, Stombaugh J, Bittinger K, Bushman FD, Costello EK, Fierer N, Pena AG, Goodrich JK, Gordon JI, et al

The etiology of MASLD is complex, with its core being the interplay between metabolic dysfunction (such as insulin resistance and dyslipidemia) and multifactorial elements (including genetics, environment and lifestyle), rather than being attributed to a single factor

These somatotrophs constitute approximately 50% of the anterior pituitary cell population and are specialized for synthesis and secretion of growth hormone (GH, also called somatotropin), a 191-amino acid peptide hormone that is one of the most important regulators of growth, metabolism, and body composition