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[3] Research published by the NIH: National Library of Medicine indicates that people with MTHFR mutations may require higher folate intake to maintain optimal homocysteine levels and overall methylation processes.[4] A study in JAMA Psychiatry suggested an association of individuals with MTHFR function and reports of mood

doi: 10.1021/jf0607314

[24] Deficiency [edit] Vitamin B 12 deficiency can potentially cause severe and irreversible damage, especially to the brain and nervous system